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Research Overview
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondrial-derived peptide encoded within mitochondrial DNA. It is a leading subject in metabolic and mitochondrial-signaling research.
Preclinical research has examined MOTS-c across glucose metabolism, insulin sensitivity, AMPK activation, and physical-performance endpoints, making it a widely referenced compound in metabolic-aging research models.
Research Focus
Mechanism (Research Context)
MOTS-c is studied for its activation of the AMPK energy-sensing pathway and its translocation to the nucleus under metabolic stress, where it is observed to regulate genes governing cellular energy balance in research models.
Intended Use
This compound is strictly intended for in vitro laboratory research. It is not for use in humans or animals. Not to be used in foods, drugs, or medical diagnostics.
Legal Disclaimer
This product has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. Usage is restricted to certified laboratories and qualified research professionals.
Terms of Sale
All sales by Codex Research are final. Buyers must be qualified professionals and assume full responsibility for safe handling and regulatory compliance. Every batch is independently verified by accredited third-party laboratories. Batch-specific Certificates of Analysis are available on our COAs page.
For Research Use Only · Not for Human Consumption
















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